本文主要研究内容
作者（2019）在《Effects of the Compound Beverage Prepared from Dates Vinegar and Garlic Juice and the Dates Vinegar on Several Diseases and Its in Vivo Mechanism Assessments》一文中研究指出：早在希波克拉底时期,醋就被用来抵抗感染和治疗其他重要疾病,在近期的研究中发现,食用醋还对糖尿病、癌症和心脏病的生物指标具有积极作用。枣引起富含活性物质,早已被民间用于对抗不同的终身疾病和癌症。通过对枣进行发酵可以制备出一种有利于消费者健康的枣醋,枣醋是一种传统的健康食品。另外,现代科学证明,大蒜具有强力杀菌、防治肿瘤、排毒清肠、降低血糖、防治心脑血病、预防感冒、抗疲劳、护肝、抗过敏等多种功能。为了克服一部分人在日常饮食中不愿意直接食用醋和大蒜的问题,本课题组研发出一种由枣醋和大蒜汁制成的复合饮料,以便于消费者方便地摄取到枣醋和大蒜中的活性组分,促进其身体健康。本文的目的就是研究枣醋/大蒜汁复合饮料和枣醋对健康的促进效果,并探索其作用机理。主要研究内容和结果如下:(1)枣醋/大蒜汁复合饮料对改善轻度高胆固醇血症成人的脂质轮廓参数和炎性标记物的影响。50名高胆固醇血症成年受试者在7周内每天饮用500 m L复合饮料或安慰剂。推荐剂量为500毫升的复合饮料可降低总胆固醇(从260.10±17.9至198.90±17.31 mg/d L)和C-反应蛋白(从8.04±1.34至4.45±1.42 mg/L),还降低了心率和平均血压,对测得的心电图参数没有显著影响。这些结果表明,该复合饮料改善了脂质和炎症生物标志物的浓度,并且有益于担心高血压的人。(2)枣醋/大蒜汁复合饮料对肥胖受试者体重、体脂肪量和血清瘦素水平的影响。85名肥胖成年在为期10周的时间里,每天在正常饮食中摄入500毫升复合饮料或安慰剂。结果表明,该复合饮料降低了体重(从73.9±6.7至69.6±5.8 kg,p=0.002)、体脂比(从29.8±5.4至28.1±4.2%,p=0.004)和血清瘦素(从36.25±3.2至31.12±3.7ng/m L,p=0.002),因此可以在代谢综合症的预防中发挥关键作用。(3)枣醋对2型糖尿病患者血液生化和血液学参数的影响。55名血糖超过126mg/d L的受试者,每天在正常饮食中摄入20 m L枣醋或安慰剂,持续10周。结果表明,枣醋改善了血液中糖化血红蛋白(从6.80±2.34至6.17±2.14(%))、空腹血糖(从171.43±36.74至147.56±38.86mg/d L,p=0.001)、总胆固醇(从218.10±16.9至191.14±14.23 mg/d L,p<0.001)、丙氨酸转氨酶(从24.94±5.03至21.88±5.85 IU/L,p=0.002)、碱性磷酸酶(从264.32±45.26至257.30±44.21 IU/L)、叶酸(从34.6±6.6至41.7±6.5 nmol/L,p<0.001)。其他血液生化和血液学因素也有所改善,但改善不显著。因此红枣醋有益于2型糖尿病患者的身体健康。(4)枣浆和枣核制成的枣醋对轻度高胆固醇血症成人血脂谱和炎症生物标志物的影响。76名总胆固醇和低密度脂蛋白胆固醇轻度升高的受试者每天在正常饮食中摄入30m L枣醋或安慰剂,持续4周。结果表明,这种枣醋显著改善了主要的血脂谱参数,总胆固醇从246.40±14.7降至197.60±14.7 mg/d L(p=0.001)、低密度脂蛋白从166.6±11.8降至109.8±11.8(p=0.001)、甘油三酯从170.30±16.54降至161.20±17.8(p=0.002)、高密度脂蛋白从41.7±8.08升至44.1±8.05(p=0.003),也显著的改善了炎症生物标志物,C-反应蛋白从7.05±1.23降至4.12±0.04 mg/L(p=0.001)、一氧化氮从31.06±0.47降至27.01±0.14μmol/L(p=0.002)、肿瘤坏死因子α从17.2±2.8降至13.6±2.4 pg/m L(p=0.001)、纤维蛋白原从272.54±22.6至238.31±11.7 mg/d L(p=0.014),表明枣醋对高血压和心悸患者有益。(5)枣醋的植物化学和理化性质初步评价研究。这部分研究的目的在于比较红枣醋、黑枣醋、市售食醋(镇江香醋(米醋)和柿子醋)之间活性的差异。为了便于分析检测,首先优化了活性物质的超声波辅助甲醇提取的条件。试验确定,利用80%和50%的甲醇超声波提取25min,可分别获得最高的酚类化合物提取率和最高的抗氧化活性。检测发现,红枣醋具有较高的总酚含量(2.57±0.16 mg GAE.m L-1),黑枣醋具有更高的总类胡萝卜素含量(3.43±0.15 mg.100 m L-1)。红枣醋和黑枣醋在理化性质上没有显著差异。红枣醋的总多酚含量远远高于市售食醋,黑枣醋的总类胡萝卜素值远远高于市售食醋,红枣醋和黑枣醋的铁还原抗氧化能力均显著高于市售食醋。这些结果表明,红枣醋无论是红色还是黑色,都有益于消费者的健康,会成为市场上具有竞争力的产品。
Abstract
zao zai xi bo ke la de shi ji ,cu jiu bei yong lai di kang gan ran he zhi liao ji ta chong yao ji bing ,zai jin ji de yan jiu zhong fa xian ,shi yong cu hai dui tang niao bing 、ai zheng he xin zang bing de sheng wu zhi biao ju you ji ji zuo yong 。zao yin qi fu han huo xing wu zhi ,zao yi bei min jian yong yu dui kang bu tong de zhong shen ji bing he ai zheng 。tong guo dui zao jin hang fa jiao ke yi zhi bei chu yi chong you li yu xiao fei zhe jian kang de zao cu ,zao cu shi yi chong chuan tong de jian kang shi pin 。ling wai ,xian dai ke xue zheng ming ,da suan ju you jiang li sha jun 、fang zhi zhong liu 、pai du qing chang 、jiang di xie tang 、fang zhi xin nao xie bing 、yu fang gan mao 、kang pi lao 、hu gan 、kang guo min deng duo chong gong neng 。wei le ke fu yi bu fen ren zai ri chang yin shi zhong bu yuan yi zhi jie shi yong cu he da suan de wen ti ,ben ke ti zu yan fa chu yi chong you zao cu he da suan zhi zhi cheng de fu ge yin liao ,yi bian yu xiao fei zhe fang bian de she qu dao zao cu he da suan zhong de huo xing zu fen ,cu jin ji shen ti jian kang 。ben wen de mu de jiu shi yan jiu zao cu /da suan zhi fu ge yin liao he zao cu dui jian kang de cu jin xiao guo ,bing tan suo ji zuo yong ji li 。zhu yao yan jiu nei rong he jie guo ru xia :(1)zao cu /da suan zhi fu ge yin liao dui gai shan qing du gao dan gu chun xie zheng cheng ren de zhi zhi lun kuo can shu he yan xing biao ji wu de ying xiang 。50ming gao dan gu chun xie zheng cheng nian shou shi zhe zai 7zhou nei mei tian yin yong 500 m Lfu ge yin liao huo an wei ji 。tui jian ji liang wei 500hao sheng de fu ge yin liao ke jiang di zong dan gu chun (cong 260.10±17.9zhi 198.90±17.31 mg/d L)he C-fan ying dan bai (cong 8.04±1.34zhi 4.45±1.42 mg/L),hai jiang di le xin lv he ping jun xie ya ,dui ce de de xin dian tu can shu mei you xian zhe ying xiang 。zhe xie jie guo biao ming ,gai fu ge yin liao gai shan le zhi zhi he yan zheng sheng wu biao zhi wu de nong du ,bing ju you yi yu dan xin gao xie ya de ren 。(2)zao cu /da suan zhi fu ge yin liao dui fei pan shou shi zhe ti chong 、ti zhi fang liang he xie qing shou su shui ping de ying xiang 。85ming fei pan cheng nian zai wei ji 10zhou de shi jian li ,mei tian zai zheng chang yin shi zhong she ru 500hao sheng fu ge yin liao huo an wei ji 。jie guo biao ming ,gai fu ge yin liao jiang di le ti chong (cong 73.9±6.7zhi 69.6±5.8 kg,p=0.002)、ti zhi bi (cong 29.8±5.4zhi 28.1±4.2%,p=0.004)he xie qing shou su (cong 36.25±3.2zhi 31.12±3.7ng/m L,p=0.002),yin ci ke yi zai dai xie zeng ge zheng de yu fang zhong fa hui guan jian zuo yong 。(3)zao cu dui 2xing tang niao bing huan zhe xie ye sheng hua he xie ye xue can shu de ying xiang 。55ming xie tang chao guo 126mg/d Lde shou shi zhe ,mei tian zai zheng chang yin shi zhong she ru 20 m Lzao cu huo an wei ji ,chi xu 10zhou 。jie guo biao ming ,zao cu gai shan le xie ye zhong tang hua xie gong dan bai (cong 6.80±2.34zhi 6.17±2.14(%))、kong fu xie tang (cong 171.43±36.74zhi 147.56±38.86mg/d L,p=0.001)、zong dan gu chun (cong 218.10±16.9zhi 191.14±14.23 mg/d L,p<0.001)、bing an suan zhuai an mei (cong 24.94±5.03zhi 21.88±5.85 IU/L,p=0.002)、jian xing lin suan mei (cong 264.32±45.26zhi 257.30±44.21 IU/L)、xie suan (cong 34.6±6.6zhi 41.7±6.5 nmol/L,p<0.001)。ji ta xie ye sheng hua he xie ye xue yin su ye you suo gai shan ,dan gai shan bu xian zhe 。yin ci gong zao cu you yi yu 2xing tang niao bing huan zhe de shen ti jian kang 。(4)zao jiang he zao he zhi cheng de zao cu dui qing du gao dan gu chun xie zheng cheng ren xie zhi pu he yan zheng sheng wu biao zhi wu de ying xiang 。76ming zong dan gu chun he di mi du zhi dan bai dan gu chun qing du sheng gao de shou shi zhe mei tian zai zheng chang yin shi zhong she ru 30m Lzao cu huo an wei ji ,chi xu 4zhou 。jie guo biao ming ,zhe chong zao cu xian zhe gai shan le zhu yao de xie zhi pu can shu ,zong dan gu chun cong 246.40±14.7jiang zhi 197.60±14.7 mg/d L(p=0.001)、di mi du zhi dan bai cong 166.6±11.8jiang zhi 109.8±11.8(p=0.001)、gan you san zhi cong 170.30±16.54jiang zhi 161.20±17.8(p=0.002)、gao mi du zhi dan bai cong 41.7±8.08sheng zhi 44.1±8.05(p=0.003),ye xian zhe de gai shan le yan zheng sheng wu biao zhi wu ,C-fan ying dan bai cong 7.05±1.23jiang zhi 4.12±0.04 mg/L(p=0.001)、yi yang hua dan cong 31.06±0.47jiang zhi 27.01±0.14μmol/L(p=0.002)、zhong liu huai si yin zi αcong 17.2±2.8jiang zhi 13.6±2.4 pg/m L(p=0.001)、qian wei dan bai yuan cong 272.54±22.6zhi 238.31±11.7 mg/d L(p=0.014),biao ming zao cu dui gao xie ya he xin ji huan zhe you yi 。(5)zao cu de zhi wu hua xue he li hua xing zhi chu bu ping jia yan jiu 。zhe bu fen yan jiu de mu de zai yu bi jiao gong zao cu 、hei zao cu 、shi shou shi cu (zhen jiang xiang cu (mi cu )he shi zi cu )zhi jian huo xing de cha yi 。wei le bian yu fen xi jian ce ,shou xian you hua le huo xing wu zhi de chao sheng bo fu zhu jia chun di qu de tiao jian 。shi yan que ding ,li yong 80%he 50%de jia chun chao sheng bo di qu 25min,ke fen bie huo de zui gao de fen lei hua ge wu di qu lv he zui gao de kang yang hua huo xing 。jian ce fa xian ,gong zao cu ju you jiao gao de zong fen han liang (2.57±0.16 mg GAE.m L-1),hei zao cu ju you geng gao de zong lei hu luo bo su han liang (3.43±0.15 mg.100 m L-1)。gong zao cu he hei zao cu zai li hua xing zhi shang mei you xian zhe cha yi 。gong zao cu de zong duo fen han liang yuan yuan gao yu shi shou shi cu ,hei zao cu de zong lei hu luo bo su zhi yuan yuan gao yu shi shou shi cu ,gong zao cu he hei zao cu de tie hai yuan kang yang hua neng li jun xian zhe gao yu shi shou shi cu 。zhe xie jie guo biao ming ,gong zao cu mo lun shi gong se hai shi hei se ,dou you yi yu xiao fei zhe de jian kang ,hui cheng wei shi chang shang ju you jing zheng li de chan pin 。
论文参考文献
论文详细介绍
论文作者分别是来自江苏大学的，发表于刊物江苏大学2019-09-19论文，是一篇关于枣醋论文,大蒜汁论文,肥胖论文,高脂血症论文,多酚论文,江苏大学2019-09-19论文的文章。本文可供学术参考使用，各位学者可以免费参考阅读下载，文章观点不代表本站观点，资料来自江苏大学2019-09-19论文网站，若本站收录的文献无意侵犯了您的著作版权，请联系我们删除。