论文摘要
精神分裂症(Schizophrenia)作为精神卫生领域中一类严重的精神疾病,是指感知觉、思维、行为的分裂,情感的不协调,以及认知功能的下降。其复发率高,社会功能损害大,生活质量影响显著,疾病负担重。目前导致精神分裂症病因仍不清楚,很多证据表明精神分裂症是一种脑结构和脑功能存在异常改变的疾病,可能有以下病因:遗传特质、宫内环境紊乱、婴儿和幼年期的生物心理社会因素。其发病机制涉及遗传、免疫、神经病理学、神经电生理、神经生化、内分泌因素、心理社会因素等各个方面。精神分裂症症状复杂多变,治疗难度大,维持治疗时间长,是精神卫生科的常见疾病,对临床上一些精神分裂症的经典病例及时整理,有助于总结诊疗体会,规范疾病临床诊治过程,有利于治疗的个体化。本文报道浙江大学医学院附属第一医院就诊的三例精神分裂症病人的诊断治疗过程并综述精神分裂症免疫学的病因研究进展。
论文目录
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