导读:本文包含了轻度先兆子痫论文开题报告文献综述及选题提纲参考文献，主要关键词:围生期结局,先兆子痫,高血压
轻度先兆子痫论文文献综述
Giannubilo,S.R,Dell'Uomo,B,Tranquilli,A.L,张旸[1]（2006）在《轻度慢性高血压妊娠并发先兆子痫的围生期结局、血压模式和风险评价》一文中研究指出Objective: Assessment of perinatal outcomes, blood pres-sure (BP) patterns and risk of superimposed preeclampsia in a population with mild chronic hypertension. Study design: We investigated 223 pregnant women with mild chronic hypertension and 200 controls. Twenty-four-hour BP monitoring longitudinally in pregnancy and Doppler assessment of uterine arteries at 24 weeks' gestation were performed. Perinatal outcomes were recorded. Results: Superimposed preeclampsia occurred in 28.4% of hypertensive women, with an increased rate of small-for-gesta-tional age babies (30.7% versus 8.9% ), a lower birth weight (2587.75 ± 832.97 versus 3167.35 ± 536.3; p < 0.001) and a higher rate of caesarean sections (69.2% versus 35.5% ) than controls. According to the ROC curve, the mean 24- h blood pressure (diastolic 78 mmHg [S.E.: 0.95; SP: 0.89]- and systolic 121 mmHg [S.E.: 0.88; SP: 0.92]) and the mean resistance index of the uterine arteries of 0.52 (S.E.: 0.69; SP: 0.87) are better prognostic values for predicting superimposed preeclampsia. Conclusions: In women with chronic hypertension in the second trimester 24 h blood pressure monitoring and Doppler velocimetry of the uterine artery are able to detect those at risk of superimposed preeclampsia. In women with circulatory adaptation to pregnancy, a good perinatal outcome is expected with proper obstetric care.(本文来源于《世界核心医学期刊文摘(妇产科学分册)》期刊2006年11期）
Robinson,C.J.,Johnson,D.D.,朱国栋[2]（2006）在《评价轻度和重度先兆子痫患者胎盘生长因子及可溶型Fms样酪氨酸激酶1受体水平》一文中研究指出Objective: The purpose of this study was to determine if maternal serum concentrations of placenta growth factor(PlGF) and soluble Fms-like tyrosine kinase 1 receptor(s-Flt1) are more abnormal in patients with severe preeclampsia compared with mild preeclampsia. Study design: Serum samples were collected from 32 control patients and 80 patients with mild or severe preeclampsia. PlGF and s-Flt1 concentrations were quantitated by enzyme-linked immunosorbent assay (ELISA). Results are expressed as median(Q1-Q3) unless stated otherwise. After normalization, serum markers were compared using one-way analysis of covariance (ANCOVA). Results: Patients with preeclampsia had decreased levels of PlGF(75.1±14 vs 391±54 pg/mL, P< .0001) and elevated s-Flt1 concentration(1081±108 vs 100.1±26.9 pg/mL, P< .0001) compared with the respective controls(mean±SEM). PlGF concentration was lower in patients with mild preeclampsia compared with severe, respectively(67 pg/mL [39-158] vs 24 pg/mL [4-57], P< .02). s-Flt1 was not different between mild and severe preeclampsia(674 pg/mL [211-1297] vs 1015 pg/mL [731-1948], P=.08). Conclusion: PlGF and s-Flt1 serum levels are abnormal in patients with preeclampsia compared with controls, but only PlGF is more abnormal in severe preeclampsia compared with mild preeclampsia.(本文来源于《世界核心医学期刊文摘(妇产科学分册)》期刊2006年10期）
华凯[3]（2004）在《硫酸镁治疗轻度先兆子痫效果的随机对比研究》一文中研究指出为明确硫酸镁是否有助于预防轻度先兆子痫进行随机对比研究。轻度先兆子痫的诊断标准:问隔6 h以上2次收缩压≥140 mmHg(1 mmHg=0.133 kPa),或舒张压≥90 mmHg,合并近期发生蛋白尿(≥1+)至少2次。慢性高血压和重度先兆子痫均除外。重度先兆子痫为:2次收缩压≥160mmHg、或舒张压≥110 mmHg,或24 h尿蛋白≥5 g,或持续头痛、视力(本文来源于《国外医学.妇产科学分册》期刊2004年02期）
[4]（2002）在《硫酸镁并不能改变轻度先兆子痫进展为重度的进程》一文中研究指出在2002年1月在美国路易斯安娜州新奥尔良市举行的第22届母亲与胎儿用药协会年会(SMFM)上,美国田纳西州大学生命科学中心Jeffrey Livingston博士报道,硫酸镁并不能延缓轻度先兆子痫进展为重度。(本文来源于《中华医学信息导报》期刊2002年03期）
轻度先兆子痫论文开题报告
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Objective: The purpose of this study was to determine if maternal serum concentrations of placenta growth factor(PlGF) and soluble Fms-like tyrosine kinase 1 receptor(s-Flt1) are more abnormal in patients with severe preeclampsia compared with mild preeclampsia. Study design: Serum samples were collected from 32 control patients and 80 patients with mild or severe preeclampsia. PlGF and s-Flt1 concentrations were quantitated by enzyme-linked immunosorbent assay (ELISA). Results are expressed as median(Q1-Q3) unless stated otherwise. After normalization, serum markers were compared using one-way analysis of covariance (ANCOVA). Results: Patients with preeclampsia had decreased levels of PlGF(75.1±14 vs 391±54 pg/mL, P< .0001) and elevated s-Flt1 concentration(1081±108 vs 100.1±26.9 pg/mL, P< .0001) compared with the respective controls(mean±SEM). PlGF concentration was lower in patients with mild preeclampsia compared with severe, respectively(67 pg/mL [39-158] vs 24 pg/mL [4-57], P< .02). s-Flt1 was not different between mild and severe preeclampsia(674 pg/mL [211-1297] vs 1015 pg/mL [731-1948], P=.08). Conclusion: PlGF and s-Flt1 serum levels are abnormal in patients with preeclampsia compared with controls, but only PlGF is more abnormal in severe preeclampsia compared with mild preeclampsia.
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轻度先兆子痫论文参考文献
[1].Giannubilo,S.R,Dell'Uomo,B,Tranquilli,A.L,张旸.轻度慢性高血压妊娠并发先兆子痫的围生期结局、血压模式和风险评价[J].世界核心医学期刊文摘(妇产科学分册).2006
[2].Robinson,C.J.,Johnson,D.D.,朱国栋.评价轻度和重度先兆子痫患者胎盘生长因子及可溶型Fms样酪氨酸激酶1受体水平[J].世界核心医学期刊文摘(妇产科学分册).2006
[3].华凯.硫酸镁治疗轻度先兆子痫效果的随机对比研究[J].国外医学.妇产科学分册.2004
[4]..硫酸镁并不能改变轻度先兆子痫进展为重度的进程[J].中华医学信息导报.2002